Degradation of 23S rRNA in Azithromycin-Treated Ribonuclease Mutants of <em>Escherichia coli</em>.
Azithromycin, a macrolide antibiotic, specifically binds to the 50S ribosomal subunit of bacterial ribosomes and inhibits translation. Azithromycin also prevents 50S ribosomal subunit assembly by binding to a 50S ribosomal subunit precursor particle. When exposed to azithromycin, several ribonucle...
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Digital Commons @ East Tennessee State University
2004
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| Online Access: | https://dc.etsu.edu/etd/957 https://dc.etsu.edu/cgi/viewcontent.cgi?article=2114&context=etd |