Development of PDIA3 and VDR Knockout Human Osteosarcoma SaOs-2 Cells Using CRISPR-Cas9

Intro: Hypovitaminosis D (vitamin D deficiency) has been observed in ageing patients with brain calcification and loss of the vitamin D receptor leads to abnormal calcification of the basal ganglia and thalamus. We have found that vitamin D can reverse calcification of human osteosarcoma SaOs-2 cell...

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Bibliographic Details
Main Authors: Pyburn, Jaeden, Keasey, Matthew
Format: Others
Published: Digital Commons @ East Tennessee State University 2020
Subjects:
VDR
Online Access:https://dc.etsu.edu/asrf/2020/presentations/59
https://dc.etsu.edu/cgi/viewcontent.cgi?article=1657&context=asrf