Immunity and Autoimmunity: Host Mimicry by HIV-1
<p>Many human monoclonal antibodies that neutralize multiple clades of HIV-1 are polyreactive and bind avidly to mammalian autoantigens. Indeed, the generation of neutralizing antibodies to the 2F5 and 4E10 epitopes of HIV-1 gp41 in man may be proscribed by immune tolerance since mice expressi...
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2015
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| Online Access: | http://hdl.handle.net/10161/9823 |