Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Regulates Hematopoietic Stem Cell Self-Renewal

<p>Hematopoietic stem cell (HSC) self-renewal, proliferation and differentiation are regulated by signaling through protein tyrosine kinases (PTK) such as c-kit, Flt-3 and Tie2. PTKs work in concert with receptor protein tyrosine phosphatases (PTPs) to maintain cellular equilibrium. The functi...

Full description

Bibliographic Details
Main Author: Quarmyne, Mamle
Other Authors: Chute, John P
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10161/9810