The Role of Otx2 in Bypassing Restrictions of Hindbrain Progenitor Cell Proliferation and the Mechanisms of its Dysregulation in Medulloblastoma

<p>Medulloblastoma is the most common malignant brain tumor in children. The understanding of the genetic alterations in this tumor is emergent, and many such genetic driver events have yet to be functionally-characterized. Our studies have sought to understand the causes and consequences of O...

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Bibliographic Details
Main Author: Wortham, Matthew
Other Authors: Yan, Hai
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10161/6158