Characterization of LpxC inhibitors and resistant mutants
<p>LpxC, the deacetylase that catalyzes the second and committed step of lipid A biosynthesis in <italic>E. coli</italic>, is an essential enzyme for virtually all Gram-negative bacteria and one of the most promising novel antibiotic targets for the treatment of multidrug-resistan...
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2012
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| Online Access: | http://hdl.handle.net/10161/6114 |