Cell-Surface GRP78 and its Antibodies: Pathologic and Therapeutic Roles in Cancer
<p>The chaperone protein GRP78 is primarily expressed in the endoplasmic reticulum, but it is also aberrantly expressed on the surface of cells under pathological conditions. One the cell membrane, GRP78 acts as a signaling molecule with unique properties. The amino-terminal domain acts as a g...
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2010
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| Online Access: | http://hdl.handle.net/10161/3805 |