Modeling the direct effects of TNFα upon drug-induced toxicity with in human, tissue-engineered myobundles.

<p>A number of significant muscle diseases, such as cachexia, sarcopenia, systemic chronic inflammation, along with inflammatory myopathies share TNFα-mediated inflammation in their pathogenesis. TNFα-based inflammatory stress may directly sensitize skeletal muscle to drug-induced toxicity. Th...

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Bibliographic Details
Main Author: Davis, Brittany
Other Authors: Truskey, George A
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10161/13357