Modeling the direct effects of TNFα upon drug-induced toxicity with in human, tissue-engineered myobundles.
<p>A number of significant muscle diseases, such as cachexia, sarcopenia, systemic chronic inflammation, along with inflammatory myopathies share TNFα-mediated inflammation in their pathogenesis. TNFα-based inflammatory stress may directly sensitize skeletal muscle to drug-induced toxicity. Th...
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2016
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Online Access: | http://hdl.handle.net/10161/13357 |