Combined Gene Therapy and Functional Tissue Engineering for the Treatment of Osteoarthritis

<p>The pathogenesis of osteoarthritis is mediated in part by inflammatory cytokines including interleukin-1 (IL-1), which promote degradation of articular cartilage and prevent human mesenchymal stem cell (hMSC) chondrogenesis. We combined gene therapy and functional tissue engineering to deve...

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Bibliographic Details
Main Author: Glass, Katherine Anne
Other Authors: Guilak, Farshid
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10161/12142