Investigatiing the Role of the Wild-Type Ras Isoforms in KRas-driven Cancer

<p>The RAS family is a group of small GTPases that can become constitutively activated by point mutations that are found in about 30% of all cancer patients. There are three well-characterized RAS family members: HRAS, NRAS, and KRAS, the latter of which is alternatively spliced at the C-ter...

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Bibliographic Details
Main Author: Weyandt, Jamie Dawn
Other Authors: Counter, Christopher M
Published: 2015
Subjects:
RAS
Online Access:http://hdl.handle.net/10161/11392