Computational Protein Design with Ensembles, Flexibility and Mathematical Guarantees, and its Application to Drug Resistance Prediction, and Antibody Design

Computational Protein Design with Ensembles, Flexibility and Mathematical Guarantees, and its Application to Drug Resistance Prediction, and Antibody Design

<p>Proteins are involved in all of life's processes and are also responsible for many diseases. Thus, engineering proteins to perform new tasks could revolutionize many areas of biomedical research. One promising technique for protein engineering is computational structure-based protein...

Full description

Bibliographic Details
Main Author: Gainza Cirauqui, Pablo
Other Authors: Donald, Bruce R.
Published: Jan
Subjects:
Computer science
Biophysics
Biochemistry
A* algorithm
antibody design
ensemble-based design
protein design
resistance prediction
simianization
Online Access:http://hdl.handle.net/10161/10468

Internet

http://hdl.handle.net/10161/10468

Similar Items