Critical evaluation of P2X7 receptor antagonists in selected seizure models
The ATP-gated P2X7 receptor (P2X7R) is a non-selective cation channel which senses high extracellular ATP concentrations and has been suggested as a target for the treatment of neuroinflammation and neurodegenerative diseases. The use of P2X7R antagonists may therefore be a viable approach for treat...
| Main Authors: | , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Universitätsbibliothek Leipzig
2016
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| Subjects: | |
| Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-206115 http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-206115 http://www.qucosa.de/fileadmin/data/qucosa/documents/20611/OAP-2016-098_Fischer_journal.pone.0156468.pdf |