The NAMPT-mediated NAD salvage pathway in cancer cell metabolism and its regulation by resveratrol
Nicotinamide adenine dinucleotide (NAD) is a key regulator of several metabolic and signaling pathways that are relevant in cancer cell survival. Cancer cells have an increased energy demand associated with an increased NAD turnover. Nicotinamide phosphoribosyltransferase (NAMPT), a key enzyme of th...
Main Author: | |
---|---|
Other Authors: | |
Format: | Doctoral Thesis |
Language: | English |
Published: |
Universitätsbibliothek Leipzig
2015
|
Subjects: | |
Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-173401 http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-173401 http://www.qucosa.de/fileadmin/data/qucosa/documents/17340/Diss_Susi_150326_final3%2BUrheberKapitel1_BIBO2.pdf |