Radiofluorinated cyclobutyl group for increased metabolic stability using tyrosine derivatives as model system
The metabolic stability of these tracers is, in addition to its affinity and selectivity, an important factor for a successful disease diagnosis. PET tracers and all other drugs are subject to biotransformation which can form metabolites as a part of the inactivation or detoxification process of the...
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| Format: | Doctoral Thesis |
| Language: | English |
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Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
2012
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| Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-99003 http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-99003 http://www.qucosa.de/fileadmin/data/qucosa/documents/9900/FRANCK2012Dissertation.pdf |