Hematopoietic Stem Cell Differentiation inside Extracellular Matrix functionalized Microcavities
The bone marrow (BM) niche provides hematopoietic stem (HSC) and progenitor cells with many exogenous cues that tightly regulate homeostasis. These cues orchestrate cellular decisions, which are difficult to dissect and analyze in vivo. This thesis introduces a novel in vitro platform that permits s...
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Format: | Doctoral Thesis |
Language: | English |
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Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
2011
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Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-68614 http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-68614 http://www.qucosa.de/fileadmin/data/qucosa/documents/6861/Ina_Diss_final.pdf |