Patched-mediated regulation of Smoothened trafficking and activity by Lipophorin-derived lipids
Hedgehog is a lipid-linked morphogen that is carried on lipoprotein particles and that regulates both patterning and proliferation in a wide variety of vertebrate and invertebrate tissues. Hyperactivity of Hedgehog signaling causes numerous forms of cancer. Hedgehog acts by binding to its receptor P...
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| Format: | Doctoral Thesis |
| Language: | English |
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Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
2011
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| Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-65291 http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-65291 http://www.qucosa.de/fileadmin/data/qucosa/documents/6529/Dissertation.pdf |