Cell culture models of Chorea Acanthocytosis and their evaluation
Chorea Acanthocytosis (ChAc) is an autosomal recessive inherited disease caused by loss- of-function mutation in the VPS13A gene which encodes CHOREIN protein. This study used induced pluripotent stem cells (iPSCs) as well as neural progenitor cells (NPCs) to generate medium spiny neurons (MSN) as w...
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| Format: | Doctoral Thesis |
| Language: | English |
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Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
2018
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| Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-235310 http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-235310 http://www.qucosa.de/fileadmin/data/qucosa/documents/23531/Cell_culture_models_of_Chorea_Acanthocystosis-SLUB_pdfa.pdf |