Cell culture models of Chorea Acanthocytosis and their evaluation

Cell culture models of Chorea Acanthocytosis and their evaluation

Chorea Acanthocytosis (ChAc) is an autosomal recessive inherited disease caused by loss- of-function mutation in the VPS13A gene which encodes CHOREIN protein. This study used induced pluripotent stem cells (iPSCs) as well as neural progenitor cells (NPCs) to generate medium spiny neurons (MSN) as w...

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Bibliographic Details
Main Author: Glaß, Hannes
Other Authors: Technische Universität Dresden, Fakultät Mathematik und Naturwissenschaften
Format: Doctoral Thesis
Language:English
Published: Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden 2018
Subjects:
Grundlagenforschung
Biomedizin
Krankheitsmodellierung
Basic research
Lifescience
Disease modelling
ddc:570
rvk:MT 12300
Neurologie
Choreoakanthozytose
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-235310
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-235310
http://www.qucosa.de/fileadmin/data/qucosa/documents/23531/Cell_culture_models_of_Chorea_Acanthocystosis-SLUB_pdfa.pdf

Internet

http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-235310
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-235310
http://www.qucosa.de/fileadmin/data/qucosa/documents/23531/Cell_culture_models_of_Chorea_Acanthocystosis-SLUB_pdfa.pdf

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