Der interzelluläre Transport Lipid-geladener Lysosomen aus Makrophagen in glatte Gefäßmuskelzellen führt zur phänotypischen Veränderung der Gefäßmuskelzellen in einen schaumzellartigen Phänotyp

AIMS: Macrophages (MPs) and vascular smooth muscle cells (VSMCs) closely interact within the growing atherosclerotic plaque. An in vitro co-culture model was established to study how MPs modulate VSMC behaviour. METHODS AND RESULTS: MPs were exposed to fluorescence-labelled-acetylated LDL (FL-acLDL...

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Bibliographic Details
Main Author: Weinert, Sönke
Other Authors: Technische Universität Dresden, Fakultät Mathematik und Naturwissenschaften
Format: Doctoral Thesis
Language:deu
Published: Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden 2015
Subjects:
LDL
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-150397
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-150397
http://www.qucosa.de/fileadmin/data/qucosa/documents/15039/Dissertation_S_Weinert_PDF_A1b_ohne_Animation.pdf