Decreased Trigeminal Sensitivity in Anosmia
The present study aimed to investigate intranasal trigeminal sensitivity in a large sample of patients with anosmia due to different etiologies. We investigated the trigeminal detection threshold for formic acid in healthy controls (n = 96) and patients with anosmia due to head trauma (n = 18) or si...
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Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
2014
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ndltd-DRESDEN-oai-qucosa.de-bsz-14-qucosa-1346042014-06-19T03:34:44Z Decreased Trigeminal Sensitivity in Anosmia Gudziol, Hilmar Schubert, Michael Hummel, Thomas Nozizeption Chemorezeptor Olfaktorische Wahrnehmung Geruchssinn Reizung Multisensorische Integration Nociception chemosensory Olfaction Irritation Multisensory integration ddc:610 rvk:XA 10000 The present study aimed to investigate intranasal trigeminal sensitivity in a large sample of patients with anosmia due to different etiologies. We investigated the trigeminal detection threshold for formic acid in healthy controls (n = 96) and patients with anosmia due to head trauma (n = 18) or sinonasal disease (n = 54). Anosmics exhibited higher thresholds compared with normosmics (p < 0.001). In addition, thresholds were found to be higher in patients with posttraumatic anosmia compared to anosmics with sinonasal disease (p < 0.001). The data indicate that (1) loss of olfactory sensitivity in humans may be associated with a decreased sensitivity towards trigeminal stimuli and (2) alteration of intranasal trigeminal function is stronger in patients with posttraumatic anosmia compared to patients with sinonasal disease. This may have implications for the medicolegal investigation of anosmic patients where trigeminal stimuli are frequently used to assess the patient’s response bias. Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden Karger, 2014-02-20 doc-type:article application/pdf http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134604 urn:nbn:de:bsz:14-qucosa-134604 PPN408049928 http://www.qucosa.de/fileadmin/data/qucosa/documents/13460/ORL2001063002072.pdf ORL 2001;63:72–75, ISSN: 0301-1569 eng |
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language |
English |
format |
Article |
sources |
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topic |
Nozizeption Chemorezeptor Olfaktorische Wahrnehmung Geruchssinn Reizung Multisensorische Integration Nociception chemosensory Olfaction Irritation Multisensory integration ddc:610 rvk:XA 10000 |
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Nozizeption Chemorezeptor Olfaktorische Wahrnehmung Geruchssinn Reizung Multisensorische Integration Nociception chemosensory Olfaction Irritation Multisensory integration ddc:610 rvk:XA 10000 Gudziol, Hilmar Schubert, Michael Hummel, Thomas Decreased Trigeminal Sensitivity in Anosmia |
description |
The present study aimed to investigate intranasal trigeminal sensitivity in a large sample of patients with anosmia due to different etiologies. We investigated the trigeminal detection threshold for formic acid in healthy controls (n = 96) and patients with anosmia due to head trauma (n = 18) or sinonasal disease (n = 54). Anosmics exhibited higher thresholds compared with normosmics (p < 0.001). In addition, thresholds were found to be higher in patients with posttraumatic anosmia compared to anosmics with sinonasal disease (p < 0.001). The data indicate that (1) loss of olfactory sensitivity in humans may be associated with a decreased sensitivity towards trigeminal stimuli and (2) alteration of intranasal trigeminal function is stronger in patients with posttraumatic anosmia compared to patients with sinonasal disease. This may have implications for the medicolegal investigation of anosmic patients where trigeminal stimuli are frequently used to assess the patient’s response bias. === Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. |
author2 |
Karger, |
author_facet |
Karger, Gudziol, Hilmar Schubert, Michael Hummel, Thomas |
author |
Gudziol, Hilmar Schubert, Michael Hummel, Thomas |
author_sort |
Gudziol, Hilmar |
title |
Decreased Trigeminal Sensitivity in Anosmia |
title_short |
Decreased Trigeminal Sensitivity in Anosmia |
title_full |
Decreased Trigeminal Sensitivity in Anosmia |
title_fullStr |
Decreased Trigeminal Sensitivity in Anosmia |
title_full_unstemmed |
Decreased Trigeminal Sensitivity in Anosmia |
title_sort |
decreased trigeminal sensitivity in anosmia |
publisher |
Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden |
publishDate |
2014 |
url |
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134604 http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134604 http://www.qucosa.de/fileadmin/data/qucosa/documents/13460/ORL2001063002072.pdf |
work_keys_str_mv |
AT gudziolhilmar decreasedtrigeminalsensitivityinanosmia AT schubertmichael decreasedtrigeminalsensitivityinanosmia AT hummelthomas decreasedtrigeminalsensitivityinanosmia |
_version_ |
1716670284439748608 |