Decreased Trigeminal Sensitivity in Anosmia

The present study aimed to investigate intranasal trigeminal sensitivity in a large sample of patients with anosmia due to different etiologies. We investigated the trigeminal detection threshold for formic acid in healthy controls (n = 96) and patients with anosmia due to head trauma (n = 18) or si...

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Main Authors: Gudziol, Hilmar, Schubert, Michael, Hummel, Thomas
Other Authors: Karger,
Format: Article
Language:English
Published: Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden 2014
Subjects:
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134604
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134604
http://www.qucosa.de/fileadmin/data/qucosa/documents/13460/ORL2001063002072.pdf
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spelling ndltd-DRESDEN-oai-qucosa.de-bsz-14-qucosa-1346042014-06-19T03:34:44Z Decreased Trigeminal Sensitivity in Anosmia Gudziol, Hilmar Schubert, Michael Hummel, Thomas Nozizeption Chemorezeptor Olfaktorische Wahrnehmung Geruchssinn Reizung Multisensorische Integration Nociception chemosensory Olfaction Irritation Multisensory integration ddc:610 rvk:XA 10000 The present study aimed to investigate intranasal trigeminal sensitivity in a large sample of patients with anosmia due to different etiologies. We investigated the trigeminal detection threshold for formic acid in healthy controls (n = 96) and patients with anosmia due to head trauma (n = 18) or sinonasal disease (n = 54). Anosmics exhibited higher thresholds compared with normosmics (p < 0.001). In addition, thresholds were found to be higher in patients with posttraumatic anosmia compared to anosmics with sinonasal disease (p < 0.001). The data indicate that (1) loss of olfactory sensitivity in humans may be associated with a decreased sensitivity towards trigeminal stimuli and (2) alteration of intranasal trigeminal function is stronger in patients with posttraumatic anosmia compared to patients with sinonasal disease. This may have implications for the medicolegal investigation of anosmic patients where trigeminal stimuli are frequently used to assess the patient’s response bias. Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden Karger, 2014-02-20 doc-type:article application/pdf http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134604 urn:nbn:de:bsz:14-qucosa-134604 PPN408049928 http://www.qucosa.de/fileadmin/data/qucosa/documents/13460/ORL2001063002072.pdf ORL 2001;63:72–75, ISSN: 0301-1569 eng
collection NDLTD
language English
format Article
sources NDLTD
topic Nozizeption
Chemorezeptor
Olfaktorische Wahrnehmung
Geruchssinn
Reizung
Multisensorische Integration
Nociception
chemosensory
Olfaction
Irritation
Multisensory integration
ddc:610
rvk:XA 10000
spellingShingle Nozizeption
Chemorezeptor
Olfaktorische Wahrnehmung
Geruchssinn
Reizung
Multisensorische Integration
Nociception
chemosensory
Olfaction
Irritation
Multisensory integration
ddc:610
rvk:XA 10000
Gudziol, Hilmar
Schubert, Michael
Hummel, Thomas
Decreased Trigeminal Sensitivity in Anosmia
description The present study aimed to investigate intranasal trigeminal sensitivity in a large sample of patients with anosmia due to different etiologies. We investigated the trigeminal detection threshold for formic acid in healthy controls (n = 96) and patients with anosmia due to head trauma (n = 18) or sinonasal disease (n = 54). Anosmics exhibited higher thresholds compared with normosmics (p < 0.001). In addition, thresholds were found to be higher in patients with posttraumatic anosmia compared to anosmics with sinonasal disease (p < 0.001). The data indicate that (1) loss of olfactory sensitivity in humans may be associated with a decreased sensitivity towards trigeminal stimuli and (2) alteration of intranasal trigeminal function is stronger in patients with posttraumatic anosmia compared to patients with sinonasal disease. This may have implications for the medicolegal investigation of anosmic patients where trigeminal stimuli are frequently used to assess the patient’s response bias. === Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
author2 Karger,
author_facet Karger,
Gudziol, Hilmar
Schubert, Michael
Hummel, Thomas
author Gudziol, Hilmar
Schubert, Michael
Hummel, Thomas
author_sort Gudziol, Hilmar
title Decreased Trigeminal Sensitivity in Anosmia
title_short Decreased Trigeminal Sensitivity in Anosmia
title_full Decreased Trigeminal Sensitivity in Anosmia
title_fullStr Decreased Trigeminal Sensitivity in Anosmia
title_full_unstemmed Decreased Trigeminal Sensitivity in Anosmia
title_sort decreased trigeminal sensitivity in anosmia
publisher Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
publishDate 2014
url http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134604
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134604
http://www.qucosa.de/fileadmin/data/qucosa/documents/13460/ORL2001063002072.pdf
work_keys_str_mv AT gudziolhilmar decreasedtrigeminalsensitivityinanosmia
AT schubertmichael decreasedtrigeminalsensitivityinanosmia
AT hummelthomas decreasedtrigeminalsensitivityinanosmia
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