Hepatitis C Virus E1E2 co-evolving networks unveil their functional dialogs and highlight original therapeutic strategies
Hepatitis C Virus (HCV) infects more than 170 million people worldwide but no vaccine is available yet. HCV entry may represent a promising target for therapies and is mediated by two envelope glycoproteins, E1 and E2, assembled as heterodimer onto the virus surface. However, how E1 and E2 dialog, s...
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| Language: | ENG |
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Ecole normale supérieure de lyon - ENS LYON
2013
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| Online Access: | http://tel.archives-ouvertes.fr/tel-00946592 http://tel.archives-ouvertes.fr/docs/00/94/65/92/PDF/DOUAM_Florian_2013_These_VD.pdf |