Hepatitis C Virus E1E2 co-evolving networks unveil their functional dialogs and highlight original therapeutic strategies

Hepatitis C Virus E1E2 co-evolving networks unveil their functional dialogs and highlight original therapeutic strategies

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Hepatitis C Virus (HCV) infects more than 170 million people worldwide but no vaccine is available yet. HCV entry may represent a promising target for therapies and is mediated by two envelope glycoproteins, E1 and E2, assembled as heterodimer onto the virus surface. However, how E1 and E2 dialog, s...

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Bibliographic Details
Main Author: Douam, Florian
Language:ENG
Published: Ecole normale supérieure de lyon - ENS LYON 2013
Subjects:
[SDV:SA] Life Sciences/Agricultural sciences
[SDV:SA] Sciences du Vivant/Sciences agricoles
Envelope glycoproteins
Hepatitis C Virus
Virus entry
Co-evolving networks
Online Access:http://tel.archives-ouvertes.fr/tel-00946592
http://tel.archives-ouvertes.fr/docs/00/94/65/92/PDF/DOUAM_Florian_2013_These_VD.pdf

Internet

http://tel.archives-ouvertes.fr/tel-00946592
http://tel.archives-ouvertes.fr/docs/00/94/65/92/PDF/DOUAM_Florian_2013_These_VD.pdf

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