HBZ-induced functional deregulation of menin - new insights into the mechanism of telomerase activation during HTLV-1-mediated leukemogenesis
Adult T-cell leukemia (ATL) is an aggressive lymphoproliferative disorder associated with human T-cell leukemia virus type 1 (HTLV-1) infection. Reactivation of telomerase, a critical event in tumor progression observed in late phases of ATL development, has been shown to be caused by HBZ (HTLV-1 bZ...
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| Language: | ENG |
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Ecole normale supérieure de lyon - ENS LYON
2013
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| Online Access: | http://tel.archives-ouvertes.fr/tel-00860179 http://tel.archives-ouvertes.fr/docs/00/86/01/79/PDF/BOROWIAK_Malgorzata_2013_these_VD.pdf |