MODELLING NUCLEOCYTOPLASMIC TRANSPORT WITH APPLICATION TO THE INTRACELLULAR DYNAMICS OF THE TUMOR SUPPRESSOR PROTEIN P53

In this thesis, I discuss two main subjects coming from biology and I propose two models that mimic the behaviours of the biological networks studied. The first part of the thesis deals with intracellular transport of molecules. Proteins, RNA and, generally, any kind of cargo molecules move freely i...

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Bibliographic Details
Main Author: Dimitrio, Luna
Language:ENG
Published: Université Pierre et Marie Curie - Paris VI 2012
Subjects:
p53
Online Access:http://tel.archives-ouvertes.fr/tel-00769901
http://tel.archives-ouvertes.fr/docs/00/76/99/01/PDF/dimitrio_tesi.pdf