Discovery and Development of Small-Molecule Modulators for the Sulfation of Glycosaminoglycans and Studying the Role of O-GlcNAc on CREB through Semisynthesis

<p>Glycosaminoglycans (GAGs) are sulfated polysaccharides that play key roles in many cellular processes, ranging from viral invasion and cancer metastasis to neuronal development. Their diverse biological activities stem from their complex sulfation patterns, which are tightly regulated in vi...

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Bibliographic Details
Main Author: Cheung, Sheldon Ting Fong
Format: Others
Published: 2017
Online Access:https://thesis.library.caltech.edu/9930/13/Thesis_Cheung5.pdf
Cheung, Sheldon Ting Fong (2017) Discovery and Development of Small-Molecule Modulators for the Sulfation of Glycosaminoglycans and Studying the Role of O-GlcNAc on CREB through Semisynthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9PR7T0K. https://resolver.caltech.edu/CaltechTHESIS:10032016-103410952 <https://resolver.caltech.edu/CaltechTHESIS:10032016-103410952>