Role of Conformational Changes in G Protein-Coupled Receptor Activation
Transmembrane signal transduction is achieved by activation of G protein-coupled receptors (GPCRs) like the human cannabinoid type 1 (CB1) receptor, the human cannabinoid type 2 (CB2) receptor, and the human mu-opioid receptor. These receptors exist in the membrane in an ensemble of conformations e...
Internet
https://thesis.library.caltech.edu/8452/1/Scott-C-E_thesis2014.pdfScott, Caitlin Eileen (2014) Role of Conformational Changes in G Protein-Coupled Receptor Activation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z94747VG. https://resolver.caltech.edu/CaltechTHESIS:05312014-002701930 <https://resolver.caltech.edu/CaltechTHESIS:05312014-002701930>