A Cocktail of Thermally Stable, Chemically Synthesized Capture Agents for the Efficient Detection of Anti-gp41 Antibodies from Human Sera and Techniques
This thesis reports on a method to improve in vitro diagnostic assays that detect immune response, with specific application to HIV-1. The inherent polyclonal diversity of the humoral immune response was addressed by using sequential in situ click chemistry to develop a cocktail of peptide-based ca...
Internet
https://thesis.library.caltech.edu/8395/61/Thesis.pdfhttps://thesis.library.caltech.edu/8395/1/CoverPage.pdf
https://thesis.library.caltech.edu/8395/2/Chapter%201.pdf
https://thesis.library.caltech.edu/8395/3/Chapter%202.pdf
https://thesis.library.caltech.edu/8395/4/Chapter%203.pdf
https://thesis.library.caltech.edu/8395/5/Chapter%204.pdf
https://thesis.library.caltech.edu/8395/28/Appendix%20A.pdf
https://thesis.library.caltech.edu/8395/33/Appendix%20B.pdf
https://thesis.library.caltech.edu/8395/39/Appendix%20C.pdf
https://thesis.library.caltech.edu/8395/49/Appendix%20D.pdf
https://thesis.library.caltech.edu/8395/54/Appendix%20E.pdf
Pfeilsticker, Jessica A. (2014) A Cocktail of Thermally Stable, Chemically Synthesized Capture Agents for the Efficient Detection of Anti-gp41 Antibodies from Human Sera and Techniques. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/0FT2-EF04. https://resolver.caltech.edu/CaltechTHESIS:05262014-170142267 <https://resolver.caltech.edu/CaltechTHESIS:05262014-170142267>