Structural requirements for catalysis: studies on RTEM-1 β-lactamase
<p>β-lactamases are a group of enzymes that confer resistance to penam and cephem antibiotics by hydrolysis of the β-lactam ring, thereby inactivating the antibiotic. Crystallographic and computer modeling studies of RTEM-1 β-lactamase have indicated that Asp 132, a strictly conserved resid...
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Format: | Others |
Language: | en |
Published: |
1994
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Online Access: | https://thesis.library.caltech.edu/7721/1/Richmond_ta_1994.pdf Richmond, Todd Alan (1994) Structural requirements for catalysis: studies on RTEM-1 β-lactamase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/bmqt-cf02. https://resolver.caltech.edu/CaltechTHESIS:05172013-094843923 <https://resolver.caltech.edu/CaltechTHESIS:05172013-094843923> |
Internet
https://thesis.library.caltech.edu/7721/1/Richmond_ta_1994.pdfRichmond, Todd Alan (1994) Structural requirements for catalysis: studies on RTEM-1 β-lactamase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/bmqt-cf02. https://resolver.caltech.edu/CaltechTHESIS:05172013-094843923 <https://resolver.caltech.edu/CaltechTHESIS:05172013-094843923>