Olefin Cyclopropanation and Carbon-Hydrogen Amination via Carbene and Nitrene Transfers Catalyzed by Engineered Cytochrome P450 Enzymes

Olefin Cyclopropanation and Carbon-Hydrogen Amination via Carbene and Nitrene Transfers Catalyzed by Engineered Cytochrome P450 Enzymes

Synthetic biology promises to transform organic synthesis by enabling artificial catalysis in living cells. I start by reviewing the state of the art in this young field and recognizing that new approaches are required for designing enzymes that catalyze nonnatural reactions, in order to expand the...

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Bibliographic Details
Main Author: Coelho, Pedro de Souza Leão
Format: Others
Published: 2013
Online Access:https://thesis.library.caltech.edu/7583/1/CoelhoPedro2013Thesis.pdf
Coelho, Pedro de Souza Leão (2013) Olefin Cyclopropanation and Carbon-Hydrogen Amination via Carbene and Nitrene Transfers Catalyzed by Engineered Cytochrome P450 Enzymes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HSPH-AF89. https://resolver.caltech.edu/CaltechTHESIS:04072013-230318757 <https://resolver.caltech.edu/CaltechTHESIS:04072013-230318757>

Internet

https://thesis.library.caltech.edu/7583/1/CoelhoPedro2013Thesis.pdf
Coelho, Pedro de Souza Leão (2013) Olefin Cyclopropanation and Carbon-Hydrogen Amination via Carbene and Nitrene Transfers Catalyzed by Engineered Cytochrome P450 Enzymes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HSPH-AF89. https://resolver.caltech.edu/CaltechTHESIS:04072013-230318757 <https://resolver.caltech.edu/CaltechTHESIS:04072013-230318757>

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