Accelerating the Interplay Between Theory and Experiment in Protein Design
<p>Protein engineering techniques such as directed evolution and structure-based design aim to improve the properties of natural proteins. The next step, the de novo insertion of function into previously inert protein scaffolds, is the lofty promise of computational protein design. In order...
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https://thesis.library.caltech.edu/6812/35/Nisthal2012_thesis.pdfhttps://thesis.library.caltech.edu/6812/2/Nisthal2012_title.pdf
https://thesis.library.caltech.edu/6812/1/Nisthal2012_Ch1.pdf
https://thesis.library.caltech.edu/6812/3/Nisthal2012_Ch2.pdf
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https://thesis.library.caltech.edu/6812/29/Nisthal2012_appendix.pdf
Nisthal, Alex (2012) Accelerating the Interplay Between Theory and Experiment in Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9833Q2F. https://resolver.caltech.edu/CaltechTHESIS:02062012-154120957 <https://resolver.caltech.edu/CaltechTHESIS:02062012-154120957>