Site specific cleavage of genomic DNA mediated by triple helix formation
<p>Physical isolation of large segments of chromosomal DNA is a major goal of human genetics. This would be greatly assisted by a generalizable technique for the cleavage of chromosomal DNA at a single site. Pyrimidine oligonucleotide directed triple helix formation is a generalizable motif fo...
Internet
https://thesis.library.caltech.edu/6659/1/Strobel_sa_1992.pdfStrobel, Scott A. (1992) Site specific cleavage of genomic DNA mediated by triple helix formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7TYF-9326. https://resolver.caltech.edu/CaltechTHESIS:09092011-112420199 <https://resolver.caltech.edu/CaltechTHESIS:09092011-112420199>