Regulation of SCF ubiquitin ligases by Jab1/Csn5 and the Cop9 signalosome

Regulation of SCF ubiquitin ligases by Jab1/Csn5 and the Cop9 signalosome

SCF ubiquitin ligases regulate the ubiquitin-dependent proteolysis of a myriad of substrate proteins, including p27, Cyclin E, and IkBa. To further gain insight into SCF regulation and function, we purified SCF from mammalian cells and found the Cop9 Signalosome associated with SCF. Interestingly, d...

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Bibliographic Details
Main Author: Cope, Gregory Allan
Format: Others
Published: 2006
Online Access:https://thesis.library.caltech.edu/2964/1/CopeThesis.pdf
Cope, Gregory Allan (2006) Regulation of SCF ubiquitin ligases by Jab1/Csn5 and the Cop9 signalosome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/43JP-NQ47. https://resolver.caltech.edu/CaltechETD:etd-07222005-141530 <https://resolver.caltech.edu/CaltechETD:etd-07222005-141530>

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https://thesis.library.caltech.edu/2964/1/CopeThesis.pdf
Cope, Gregory Allan (2006) Regulation of SCF ubiquitin ligases by Jab1/Csn5 and the Cop9 signalosome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/43JP-NQ47. https://resolver.caltech.edu/CaltechETD:etd-07222005-141530 <https://resolver.caltech.edu/CaltechETD:etd-07222005-141530>

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