Development of a Structure Prediction Method for G-Protein Coupled Receptors
<p>G-Protein Coupled Receptors (GPCRs) form a major target class of membrane proteins for therapeutic drug design, and the challenge is to design subtype specific drugs. Hence the knowledge of three-dimensional structure is critical to drug design for GPCRs. Since GPCRs are membrane bound prot...
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https://thesis.library.caltech.edu/2361/10/Thesis-TOC.pdfhttps://thesis.library.caltech.edu/2361/9/Thesis-Intro.pdf
https://thesis.library.caltech.edu/2361/4/Thesis-Chapter1.pdf
https://thesis.library.caltech.edu/2361/5/Thesis-Chapter2.pdf
https://thesis.library.caltech.edu/2361/6/Thesis-Chapter3.pdf
https://thesis.library.caltech.edu/2361/7/Thesis-Chapter4.pdf
https://thesis.library.caltech.edu/2361/8/Thesis-Chapter5.pdf
https://thesis.library.caltech.edu/2361/1/Thesis-AppendixA.pdf
https://thesis.library.caltech.edu/2361/2/Thesis-AppendixB.pdf
https://thesis.library.caltech.edu/2361/3/Thesis-AppendixC.pdf
Hall, Spencer Eugene (2005) Development of a Structure Prediction Method for G-Protein Coupled Receptors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/JN28-5F55. https://resolver.caltech.edu/CaltechETD:etd-06012005-235052 <https://resolver.caltech.edu/CaltechETD:etd-06012005-235052>