The Construction and Kinetic Analysis of Specific Mutants of β-Lactamase
<p>Mutants of RTEM-1 β-lactamase, an enzyme responsible for bacterial resistance to β-lactam antibiotics, have been constructed by cassette mutagenesis. β-Lactamases have been classified into three groups based on catalytic and structural similarities. Class A B-lactamases, of which the RTEM-1...
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Format: | Others |
Language: | en |
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1987
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Online Access: | https://thesis.library.caltech.edu/11776/2/Carroll_SS_1987.pdf Carroll, Steven S. (1987) The Construction and Kinetic Analysis of Specific Mutants of β-Lactamase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2mg4-x771. https://resolver.caltech.edu/CaltechTHESIS:08302019-102809124 <https://resolver.caltech.edu/CaltechTHESIS:08302019-102809124> |
Internet
https://thesis.library.caltech.edu/11776/2/Carroll_SS_1987.pdfCarroll, Steven S. (1987) The Construction and Kinetic Analysis of Specific Mutants of β-Lactamase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2mg4-x771. https://resolver.caltech.edu/CaltechTHESIS:08302019-102809124 <https://resolver.caltech.edu/CaltechTHESIS:08302019-102809124>