Targeted Nanoparticle Delivery of Therapeutics Across the Blood-Brain and Blood-Tumor Barriers to Breast Cancer Brain Metastases

Targeted Nanoparticle Delivery of Therapeutics Across the Blood-Brain and Blood-Tumor Barriers to Breast Cancer Brain Metastases

<p>Brain metastases of human epidermal growth factor receptor 2 (HER2)-positive breast cancer are presenting an increasing problem in the clinic. While HER2-targeted therapies effectively control systemic disease, their efficacy against brain metastases is hindered by their inability to penetr...

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Bibliographic Details
Main Author: Wyatt, Emily Ann
Format: Others
Language:en
Published: 2018
Online Access:https://thesis.library.caltech.edu/11033/26/Wyatt_Emily_A_Thesis_121018_for_Release.pdf
Wyatt, Emily Ann (2018) Targeted Nanoparticle Delivery of Therapeutics Across the Blood-Brain and Blood-Tumor Barriers to Breast Cancer Brain Metastases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5qpd-0736. https://resolver.caltech.edu/CaltechTHESIS:06062018-180959061 <https://resolver.caltech.edu/CaltechTHESIS:06062018-180959061>

Internet

https://thesis.library.caltech.edu/11033/26/Wyatt_Emily_A_Thesis_121018_for_Release.pdf
Wyatt, Emily Ann (2018) Targeted Nanoparticle Delivery of Therapeutics Across the Blood-Brain and Blood-Tumor Barriers to Breast Cancer Brain Metastases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5qpd-0736. https://resolver.caltech.edu/CaltechTHESIS:06062018-180959061 <https://resolver.caltech.edu/CaltechTHESIS:06062018-180959061>

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