Revealing the Mechanism of Xist-mediated Silencing
<p>Xist initiates XCI by spreading across the future inactive X-chromosome, excluding RNA polymerase II, recruiting the polycomb repressive complex and its associated repressive chromatin modifications, and repositioning active genes into a transcriptionally silenced nuclear compartment. While...
Internet
https://thesis.library.caltech.edu/10551/1/ThesisMergeAll_PR.pdfChen, Chun-Kan (2018) Revealing the Mechanism of Xist-mediated Silencing. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z94J0C9J. https://resolver.caltech.edu/CaltechTHESIS:11032017-102218314 <https://resolver.caltech.edu/CaltechTHESIS:11032017-102218314>