Design, synthesis and pharmacological evaluation of pyrimidobenzothiazole-3-carboxylate derivatives as selective L-type calcium channel blockers

Design, synthesis and pharmacological evaluation of pyrimidobenzothiazole-3-carboxylate derivatives as selective L-type calcium channel blockers

No === L-type voltage gated calcium channels play essential role in contraction of various skeletal and vascular smooth muscles, thereby plays important role in regulating blood pressure. Dihydropyridine receptors have been targeted for development of newer antihypertensive agents, one of the struct...

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Main Authors: Chikhale, R., Thorat, S., Pant, A., Jadhav, A., Thatipamula, K.C., Bansode, Ratnadeep V., Bhargavi, G., Karodia, Nazira, Rajasekharan, M.V., Paradkar, Anant R., Khedekar, Pramod
Published: 2016
Subjects:
3d-qsar
Ace
Benzothiazole
Hypertension
Myosin light chain kinase
Online Access:http://hdl.handle.net/10454/9327

Internet

http://hdl.handle.net/10454/9327

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