The polyunsaturated fatty acids, EPA and DPA exert a protective effect in the hippocampus of the aged rat

The polyunsaturated fatty acids, EPA and DPA exert a protective effect in the hippocampus of the aged rat

no === Age is characterized by deficits in synaptic function identified by decreased performance of aged animals in spatial learning tasks and reduced ability of animals to sustain long-term potentiation (LTP). Several cellular and molecular events are correlated with these deficits, many of which...

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Bibliographic Details
Main Authors: Kelly, L.E., Grehan, B., Chiesa, A.D., O'Mara, S.M., Downer, E., Sahyoun, George, Massey, Karen A., Nicolaou, Anna, Lynch, M.A.
Language:en
Published: 2010
Subjects:
Age and aging
Hippocampus
Synaptic function
Long term potentiation (LTP)
Polyunsaturated fatty acids
Ceramide
Reactive oxygen species
Spatial learning
Online Access:http://hdl.handle.net/10454/4583

Internet

http://hdl.handle.net/10454/4583

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