Effect of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid on E-type prostaglandin synthesis and EP4 receptor signalling in human colorectal cancer cells.

The omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA), in the free fatty acid (FFA) form, has been demonstrated to reduce adenoma number and size in patients with familial adenomatous polyposis. However, the mechanistic basis of the antineoplastic activity of EPA in the colorectum remai...

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Bibliographic Details
Main Authors: Hawcroft, Gillian, Loadman, Paul M., Belluzzi, Andrea, Hull, Mark A.
Language:en
Published: Neoplasia Press 2010
Subjects:
EP4
Online Access:http://hdl.handle.net/10454/4551