The lysosomal protease cathepsin L is an important regulator of keratinocyte and melanocyte differentiation during hair follicle morphogenesis and cycling.

No === We have previously shown that the ubiquitously expressed lysosomal cysteine protease, cathepsin L (CTSL), is essential for skin and hair follicle homeostasis. Here we examine the effect of CTSL deficiency on hair follicle development and cycling in ctsl-/- mice by light and electron microscop...

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Bibliographic Details
Main Authors: Tobin, Desmond J., Foitzik, K., Reinheckel, T.T., Hecklenberg, L., Botchkarev, Vladimir A., Peters, S.C., Paus, R.
Language:en
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10454/3823