Effects of caffeine on potassium currents in isolated rat ventricular myocytes

No === Rapid exposure of cardiac muscle to high concentrations of caffeine releases Ca 2+ from the sarcoplasmic reticulum (SR). This Ca 2+ is then extruded from the cell by the Na +/Ca 2+ exchanger. Measurement of the current carried by the exchanger ( I Na/Ca) can therefore be used to estimate of t...

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Bibliographic Details
Main Authors: Hussain, Munir, Chorvatova, A.
Language:en
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10454/3003