Targeting the TGF-β signaling pathway for resolution of pulmonary arterial hypertension
Yes === Aberrant transforming growth factor-β (TGF-β) signaling activation is linked to pulmonary arterial hypertension (PAH). BMPR2 mutations perturb the balance between bone morphogenetic protein (BMP) and TGF-β pathways, leading to vascular remodeling, narrowing of the lumen of pulmonary vasculat...
| Main Authors: | , , |
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| Language: | en |
| Published: |
2021
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10454/18507 |