PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma

PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma

No === Neoadjuvant chemoradiotherapy (neo-CRT) prior to surgery is the standard of care for oesophageal adenocarcinoma (OAC) patients. Unfortunately, most patients fail to respond to treatment. MiR-187 was previously shown to be downregulated in neo-CRT non-responders, whist in vitro miR-187 overexp...

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Bibliographic Details
Main Authors: Edge, S.D., Renard, I., Pyne, E., Moody, Hannah L., Roy, R., Beavis, A.W., Archibald, S.J., Cawthorne, C.J., Maher, S.G., Pires, I.M.
Language:en
Published: 2021
Subjects:
Oesophageal adenocarcinoma
PI3K inhibition
Neoadjuvant chemoradiotherapy
Online Access:http://hdl.handle.net/10454/18357

Internet

http://hdl.handle.net/10454/18357

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