An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors

Yes === The polysialyltransferases (polySTs) catalyse the polymerisation of polysialic acid, which plays an important role in tumour metastasis. While assays are available to assess polyST enzyme activity, there is no methodology available specifically optimised for identification and quantitative e...

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Bibliographic Details
Main Authors: Guo, Xiaoxiao, Malcolm, Jodie R., Ali, Marrwa M., Ribeiro Morais, Goreti, Shnyder, Steven D., Loadman, Paul M., Patterson, Laurence H., Falconer, Robert A.
Language:en
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10454/17821