Specific gyrA gene mutations predict poor treatment outcome in MDR-TB

Specific gyrA gene mutations predict poor treatment outcome in MDR-TB

Yes === Mutations in the gyrase genes cause fluoroquinolone resistance in Mycobacterium tuberculosis. However, the predictive value of these markers for clinical outcomes in patients with MDR-TB is unknown to date. The objective of this study was to determine molecular markers and breakpoints predic...

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Bibliographic Details
Main Authors: Rigouts, L., Coeck, N., Gumusboga, M., de Rijk, W.B., Aung, K.J., Hossain, M.A., Fissette, K., Rieder, H.L., Meehan, Conor J., de Jong, B.C., Van Deun, A.
Language:en
Published: 2019
Subjects:
Mutation
Bangladesh
Genes
Ofloxacin
Tuberculosis
Treatment outcome
Multidrug-resistant tuberculosis
Gatifloxacin
Moxifloxacin
Malnutrition-inflammation-cachexia syndrome
Online Access:http://hdl.handle.net/10454/17328

Internet

http://hdl.handle.net/10454/17328

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