Tumor growth suppression using a combination of taxol-based therapy and GSK3 inhibition in non-small cell lung cancer

Tumor growth suppression using a combination of taxol-based therapy and GSK3 inhibition in non-small cell lung cancer

Yes === Glycogen synthase kinase-3 (GSK3) is over-expressed and hyperactivated in non-small cell lung carcinoma (NSCLC) and plays a role in ensuring the correct alignment of chromosomes on the metaphase plate during mitosis through regulation of microtubule stability. This makes the enzyme an attrac...

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Bibliographic Details
Main Authors: O'Flaherty, L., Shnyder, Steven D., Cooper, Patricia A., Cross, S.J., Wakefield, J.G., Pardo, O.E., Seckl, M.J., Tavare, J.M.
Language:en
Published: 2019
Subjects:
Tumor growth suppression
GSK3 inhibition
Taxol
Non-small cell lung carcinoma
Cancer therapy
Online Access:http://hdl.handle.net/10454/17021

Internet

http://hdl.handle.net/10454/17021

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