Endocytosis of hERG Is Clathrin-Independent and Involves Arf6

Endocytosis of hERG Is Clathrin-Independent and Involves Arf6

yes === The hERG potassium channel is critical for repolarisation of the cardiac action potential. Reduced expression of hERG at the plasma membrane, whether caused by hereditary mutations or drugs, results in long QT syndrome and increases the risk of ventricular arrhythmias. Thus, it is of fundame...

Full description

Bibliographic Details
Main Authors: Karnik, R., Ludlow, M.J., Abuarab, N., Smith, A.J., Hardy, Matthew E., Elliott, D.J.S., Sivaprasadarao, A.
Language:en
Published: 2018
Subjects:
hERG potassium channel
Cardiac action potential
Endocytosis
Clathrin-independent endocytosis
Arf6
Online Access:http://hdl.handle.net/10454/16506

Internet

http://hdl.handle.net/10454/16506

Similar Items