A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K+ channels in carbon monoxide–induced proarrhythmic early afterdepolarizations

yes === Exposure to CO causes early afterdepolarization arrhythmias. Previous studies in rats have indicated that arrhythmias arose as a result of augmentation of the late Na+ current. The purpose of the present study was to examine the basis for CO-induced arrhythmias in guinea pig myocytes in whic...

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Bibliographic Details
Main Authors: Al-Owais, M.M., Hettiarachchi, N.T., Kirton, H.M., Hardy, Matthew E., Boyle, J.P., Scragg, J.L., Steele, D.S., Peers, C.
Language:en
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10454/16500