Development of Peptide Cyclization Strategies for Their Incorporation into One-Bead-One-Compound Peptide Libraries
Thesis advisor: Jianmin Gao === Thesis advisor: Eranthie Weerapana === Cyclic peptides provide a privileged scaffold when optimizing interactions with various biological targets. Their rigidified structure decreases the entropic cost of binding by preorganizing residues in a fixed conformation, whic...
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| Format: | Others |
| Language: | English |
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Boston College
2015
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| Online Access: | http://hdl.handle.net/2345/bc-ir:104934 |