Study of Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase

Thesis advisor: Evan R. Kantrowitz === For nearly 60 years the ATP activation and the CTP inhibition of Escherichia coli aspartate transcarbamoylase (ATCase) has been the textbook example of allosteric regulation. We present kinetic data and 5 X-ray structures determined in the absence and presence...

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Bibliographic Details
Main Author: Zheng, Yunan
Format: Others
Language:English
Published: Boston College 2013
Subjects:
Online Access:http://hdl.handle.net/2345/3683